Russell Brand was a ruthless, calculated and manipulative sexual predator who boasted about wanting to have sex with 5,000 women, a court has heard. This was reported by Qazaqyia.kz citing The Guardian.

The 51-year-old comedian is accused of having an "insatiable desire" to get what he wanted and treating women as a means to an end.

He allegedly ignored one woman's pleas to stop raping her in an assault that left her bleeding and in pain. He is also accused of having raped another woman as he told her: "Oh come on, don't be a spoilsport."

Brand faces three charges of rape, three of sexual assault and one of indecent assault against six women, in allegations spanning 10 years from 1999 to 2009. He denies all the charges and has pleaded not guilty.

Wearing a black pinstripe suit, a black and white shirt and a necktie, Brand stood in the dock at Southwark crown court in London on Wednesday as the prosecution opened its case.

The prosecutor, Riel Karmy-Jones KC, told jurors: "The circumstances of the offending were as wide and as varied as the defendant's career. Offending took place in a number of locations: a hotel room, workplaces, a toilet cubicle in a bar and at his home address."

"Some of the women involved protested and said no, others had no opportunity to protest and no opportunity to react to his advances but that didn't matter to the defendant. Regardless of who they were and what they said or did, Russell Brand was not deterred."

"His desire, strong desire, for some form of sexual contact was indiscriminate and voracious. He could be nice when he wanted to be – funny undoubtedly, charming, likable even when he wanted something in return, but then demanding, entitled, a flirt with a huge sexual appetite, childlike in his expectation that his every desire should be met."

"He was ruthless, he was calculated and manipulative, and the prosecution say, he was a sexual predator."

She said Brand had told a former flatmate, Mark Pinheiro, that he wanted to sleep with 5,000 women in his lifetime and had strategies to achieve that aim, allegedly saying: "All you have to do is tell them what they need to hear."

The court heard the earliest allegation dated back to the 1999 Labour party conference in Bournemouth, when Brand was not yet famous. He allegedly raped a woman at a hotel after meeting her at a fringe cabaret show where he was performing.

He is accused of stripping off his clothes and performing Basil Fawlty-style silly walks like an ostrich before the attack.

"She remembers the weight of him on top of her, she couldn't move, she was finding it hard to breathe, but she recalls trying not to let him kiss her, and saying 'no'," the prosecutor said.

"She knows that he groped her, was touching her, he grabbed her breasts, he was trying to kiss her, he was putting his fingers in her mouth and doing things with his tongue that were horrible, like a lizard."

Brand allegedly raped her without a condom, before telling her: "Don't worry, I get tested regularly for STDs, I don't have anything." He then behaved as if nothing had happened, wrote down his email address, and said he had to get back to his mother.

He denied the allegation in a prepared statement to police, saying he had had sexual encounters in countless locations and scenarios, often with people he had just met.

Giving evidence on Wednesday afternoon, Pinheiro, who had also performed in the cabaret, told jurors that Brand had said he was "going to go and get laid" when their final show ended. He added that Brand appeared "discombobulated" the next day and was eager to leave Bournemouth. Pinheiro said Brand eventually told him about having had sex with a woman, and said he made the comment: "I think I may have gone a bit too far."

Under cross-examination by Brand's defence barrister Ian Winter KC, Pinheiro was questioned about the reliability of his account but insisted he had merely described Brand's behaviour.

Brand's celebrity status was growing by the time of the second allegation in 2001, as was his "sense of entitlement to have what he wanted whenever he wanted it", the prosecutor said.

The second complainant was working at MTV when she offered to show Brand to the toilets where he allegedly indecently assaulted her. Brand is accused of grabbing the woman by the forearm and trying to pull her into the male toilets. He had what she described as a desperate, wild-eyed look on his face, as he said: "Please, please come in – oh go on."

She was shocked and mentioned what had happened when she returned from the toilet but never formally reported it.

The third woman had attended a friend's birthday at a bar in Soho in London in 2004 when Brand allegedly sexually assaulted her by grabbing and squeezing her breasts with a "big, weird grin" on his face. He then grabbed her arm and pulled her into the toilets where he orally raped her, the court heard. The prosecutor said: "As she was saying: 'What are you doing? I don't want to do this,' he just said: 'Oh come on, don't be a spoilsport. You want to.'"

The fourth woman was working at a radio station when she alleged that Brand "sloppily and aggressively" kissed her and grabbed her breasts and buttocks in a sexual assault alleged to have taken place in 2004 or 2005.

She pushed him away and told him to "fuck off" to which Brand sniggered. "These women meant nothing to him and perhaps he found their protestations amusing, funny?" the prosecutor said.

The fifth woman also features in the allegations.